Transdermal nitroglycerin patch therapy improves left ventricular function and prevents remodeling after acute myocardial infarction: Results of a multicenter prospective randomized, double-blind, placebo-controlled trial Academic Article uri icon

Overview

MeSH Major

  • Myocardial Infarction
  • Nitroglycerin
  • Vasodilator Agents
  • Ventricular Function, Left

abstract

  • Transdermal NTG patches prevent LV dilation in patients surviving AMI. The beneficial effects are limited to patients with depressed LV function and only at the lowest (0.4-mg/h) dose. Continued administration is necessary to maintain efficacy. Whether these remodeling effects confer a clinical or survival advantage will need to be addressed in an adequately powered cardiac event trial.

publication date

  • May 26, 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9610531

Additional Document Info

start page

  • 2017

end page

  • 24

volume

  • 97

number

  • 20