In vivo expression of transforming growth factor-β1 in humans: Stimulation by cyclosporine Academic Article Article uri icon

Overview

MeSH Major

  • Stomach Neoplasms

abstract

  • Our first-time demonstration of a TGF-beta1-selective in vivo stimulatory effect of CsA in humans: (1) advances a TGF-beta1-centered hypothesis for the beneficial (immunosuppression) and detrimental (fibrosis, hypertension) effects of CsA use, and (2) broadens the mechanism of immunosuppressive action of CsA to include heightened expression of an endogenous immunosuppressive cytokine.

publication date

  • February 15, 1998

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1097/00007890-199802150-00003

PubMed ID

  • 9484745

Additional Document Info

start page

  • 313

end page

  • 8

volume

  • 65

number

  • 3