Class restriction of cephalosporin use to control total cephalosporin resistance in nosocomial Klebsiella Academic Article Article uri icon

Overview

MeSH Major

  • Anti-Infective Agents
  • Antibiotic Prophylaxis
  • Drug Resistance, Multiple, Bacterial
  • Escherichia coli Infections
  • Image-Guided Biopsy
  • Prostate
  • Ultrasonography, Interventional
  • beta-Lactams

abstract

  • Extensive cephalosporin class restriction significantly reduced nosocomial, plasmid-mediated, cephalosporin-resistant Klebsiella infection and colonization. This occurred at the price of increased imipenem resistance in P aeruginosa, which remained susceptible to other agents. Thus, an overall reduction in multiply-resistant pathogens was achieved within 1 year.

publication date

  • October 14, 1998

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1001/jama.280.14.1233

PubMed ID

  • 9786372

Additional Document Info

start page

  • 1233

end page

  • 7

volume

  • 280

number

  • 14