Complete remission after treatment of acute promyelocytic leukemia with arsenic trioxide Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents
  • Arsenicals
  • Leukemia, Promyelocytic, Acute
  • Oxides

abstract

  • Low doses of arsenic trioxide can induce complete remissions in patients with APL who have relapsed. The clinical response is associated with incomplete cytodifferentiation and the induction of apoptosis with caspase activation in leukemic cells.

publication date

  • November 5, 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJM199811053391901

PubMed ID

  • 9801394

Additional Document Info

start page

  • 1341

end page

  • 8

volume

  • 339

number

  • 19