Results of retroviral and adenoviral approaches to cancer gene therapy. Review uri icon

Overview

MeSH

  • Female
  • Granulocyte Colony-Stimulating Factor
  • Hematopoietic Stem Cell Mobilization
  • Humans

MeSH Major

  • Adenoviridae
  • Breast Neoplasms
  • Gene Transfer Techniques
  • Genes, MDR
  • Genetic Therapy
  • Genetic Vectors
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells
  • Neoplasms
  • Ovarian Neoplasms
  • P-Glycoprotein
  • Retroviridae

abstract

  • Genetic modification for cancer treatment has involved the introduction of chemotherapy protection and sensitization genes into normal and tumor cells, respectively, for the purpose of improving the outcome of conventional approaches to the treatment of solid tumor neoplasms. This paper will review the use of multidrug resistance-1 retroviral vectors and cytosine deaminase adenoviral prodrug activation vectors for this purpose.

publication date

  • 1998

has subject area

  • Adenoviridae
  • Breast Neoplasms
  • Female
  • Gene Transfer Techniques
  • Genes, MDR
  • Genetic Therapy
  • Genetic Vectors
  • Granulocyte Colony-Stimulating Factor
  • Hematopoietic Stem Cell Mobilization
  • Hematopoietic Stem Cell Transplantation
  • Hematopoietic Stem Cells
  • Humans
  • Neoplasms
  • Ovarian Neoplasms
  • P-Glycoprotein
  • Retroviridae

Research

keywords

  • Journal Article
  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/stem.5530160830

PubMed ID

  • 11012168

Additional Document Info

start page

  • 247

end page

  • 250

volume

  • 16 Suppl 1