Differential expression of heat shock proteins in normal and failing human hearts Academic Article uri icon

Overview

MeSH Major

  • Cardiomyopathy, Dilated
  • HSP70 Heat-Shock Proteins
  • Heat-Shock Proteins
  • Myocardial Ischemia
  • Myocardium

abstract

  • This study shows for the first time that differential changes in hsp levels occur in end-stage heart failure. Since hsps can render cells resistant to apoptosis, and are associated with the mitochondria and the cytoskeleton, which are known to be abnormal in heart failure, these studies may lead to new insights into the pathogenesis of cardiac decompensation.

publication date

  • April 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1006/jmcc.1998.0646

PubMed ID

  • 9602430

Additional Document Info

start page

  • 811

end page

  • 8

volume

  • 30

number

  • 4