Treatment of patients with acute lymphoblastic leukemia with bulky extramedullary disease and T-cell phenotype or other poor prognostic features: Randomized controlled trial from the Children's Cancer Group Academic Article Article uri icon

Overview

MeSH Major

  • Kidney Neoplasms
  • Wilms Tumor

abstract

  • The adverse prognostic implications of lymphomatous ALL can be minimized by the NY and BFM regimens. Cranial irradiation resulted in better CNS disease control when added to the LSA2-L2 regimen, but did not improve the overall disease free survival. With improved systemic chemotherapy, there was no excess of lymph node, testicular, or other local recurrence without prophylactic irradiation to sites of initial bulk disease or to the testes.

publication date

  • February 1998

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1002/(SICI)1097-0142(19980201)82:3<600::AID-CNCR24>3.0.CO;2-4

PubMed ID

  • 9452280

Additional Document Info

start page

  • 600

end page

  • 12

volume

  • 82

number

  • 3