Timing algorithm for bolus chase MR digital subtraction angiography Academic Article Article uri icon


MeSH Major

  • Lower Extremity
  • Mass Screening
  • Venous Insufficiency


  • To acquire multiple longitudinal locations in the lower extremity after a single contrast injection, appropriate table translation and contrast injection are required. An approximate model based on constant bolus velocity was developed to describe the space-time course of a contrast bolus in the lower extremity. This model was verified in dynamic MR angiograms acquired in a group of patients using time-resolved 2D MR digital subtraction angiography (MRDSA). From this contrast bolus passage model, a timing algorithm for table translation and contrast injection was developed for bolus chase MRDSA, subsequently validated in bolus chase 2D MRDSA experiments. All targeted major peripheral arteries were well depicted in bolus chase 2D MRDSA using this timing algorithm and a single 15-ml contrast dose.

publication date

  • January 1998



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/mrm.1910390504

PubMed ID

  • 9581598

Additional Document Info

start page

  • 691

end page

  • 6


  • 39


  • 5