Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart Academic Article uri icon

Overview

MeSH Major

  • Enterocolitis, Necrotizing
  • Infant, Premature
  • Infant, Premature, Diseases

abstract

  • An Ad vector expressing the VEGF121 cDNA induces collateral vessel development in ischemic myocardium and results in significant improvement in both myocardial perfusion and function. Such a strategy may be useful in patients with ischemic heart disease in whom complete revascularization is not possible.

publication date

  • January 1998

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0022-5223(98)70455-6

Additional Document Info

start page

  • 168

end page

  • 76; discussion 176-7

volume

  • 115

number

  • 1