Allogeneic peripheral-blood progenitor-cell transplantation for poor- risk patients with metastatic breast cancer Academic Article uri icon

Overview

MeSH Major

  • Bone Neoplasms
  • Breast Neoplasms
  • Hematopoietic Stem Cell Transplantation
  • Liver Neoplasms

abstract

  • We conclude that allogeneic PBPC transplantation is a feasible procedure for patients with poor-risk metastatic breast cancer. The regression of tumor associated with GVHD provides suggestive clinical evidence that graft-versus-tumor effects may occur against breast cancer. Compared with autologous transplantation, allogeneic PBPC transplantation is associated with the additional risks of GVHD and related infections. Allogeneic transplantation should only be performed in the context of clinical trials and its ultimate role requires demonstration of improved progression-free survival.

publication date

  • March 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9508181

Additional Document Info

start page

  • 986

end page

  • 93

volume

  • 16

number

  • 3