High-dose induction chemoradiotherapy followed by autologous bone marrow transplantation as consolidation therapy in rhabdomyosarcoma, extraosseous Ewing's sarcoma, and undifferentiated sarcoma Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Bone Marrow Transplantation
  • Neoplasms, Germ Cell and Embryonal
  • Rhabdomyosarcoma
  • Sarcoma, Ewing

abstract

  • Consolidation of response by myeloablative chemotherapy was well tolerated. Split-course hyperfractionated radiotherapy did not increase the rate of local control. The results of this short-course therapy were comparable to previous therapies of 1 to 2 years' duration. Induction and consolidation chemotherapy, as well as radiation dose, could be further intensified, since no death due to toxicity occurred among these patients.

publication date

  • May 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9586881

Additional Document Info

start page

  • 1697

end page

  • 706

volume

  • 16

number

  • 5