Persistent alterations of the autonomic nervous system after noncardiac surgery Academic Article Article uri icon

Overview

MeSH Major

  • Heptanoic Acids
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Pneumonectomy
  • Postoperative Complications
  • Pyrroles

abstract

  • Persistent downregulation and desensitization of the lymphocyte betaAR/adenylyl cyclase system correlated with decrements in time and frequency domain indices of HRV throughout the first week after major abdominal or thoracic surgery. These physiologic alterations suggest the continued presence of adaptive autonomic regulatory mechanisms and may explain why the at-risk period after major surgery appears to be about 1 week or more.

publication date

  • July 1998

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1097/00000542-199807000-00008

PubMed ID

  • 9667291

Additional Document Info

start page

  • 30

end page

  • 42

volume

  • 89

number

  • 1