Culture substrate-specific expression of P2Y2 receptors in distal lung epithelial cells isolated from foetal rats Academic Article uri icon

Overview

MeSH Major

  • Epithelial Cells
  • Lung
  • Receptors, Purinergic P2

abstract

  • ATP and UTP did not evoke [Ca2+]i signals in rat foetal lung epithelial cells grown on glass but elicited clear responses in cells grown into functionally polarised epithelia on permeable supports. Moreover, P2Y2 receptor mRNA could not be detected in cells on glass by the polymerase chain reaction but this mRNA species was clearly expressed by polarised cells. P2Y2 receptor expression thus appears to be a feature of the polarised phenotype.

publication date

  • January 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC1565477

Digital Object Identifier (DOI)

  • 10.1038/sj.bjp.0701942

PubMed ID

  • 9692767

Additional Document Info

start page

  • 845

end page

  • 7

volume

  • 124

number

  • 5