Tolerability of oral loading of divalproex sodium in the treatment of acute mania Academic Article uri icon

Overview

MeSH Major

  • Antimanic Agents
  • Bipolar Disorder
  • Valproic Acid

abstract

  • A divalproex dosage strategy beginning with 30 mg/kg/day for 2 days, followed by 20 mg/kg/day thereafter, was reasonably well tolerated in this group of acutely manic patients, even with the concurrent use of other psychotropic medications. Blood levels of 56 to 124 mcg/ml were observed within 3 days after initiating treatment.

publication date

  • June 3, 1998

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/(SICI)1520-6394(1998)7:2<83::AID-DA6>3.0.CO;2-6

PubMed ID

  • 9614597

Additional Document Info

start page

  • 83

end page

  • 6

volume

  • 7

number

  • 2