Role of axillary lymph node dissection after tumor downstaging with induction chemotherapy for locally advanced breast cancer Academic Article uri icon


MeSH Major

  • Breast Neoplasms
  • Lymph Node Excision
  • Lymph Nodes


  • Preoperative clinical assessment of the axilla by physical examination combined with ultrasound examination is not completely accurate in predicting metastases in patients with LABC following tumor downstaging. However, patients with negative findings on both physical and ultrasound examinations of the axilla may be potential candidates for omission of axillary dissection if the axilla will be irradiated because minimal axillary disease remains. Patients who have positive findings on preoperative physical or ultrasound examinations should receive axillary dissection to ensure local control. A prospective randomized trial of axillary dissection versus axillary radiotherapy in patients with a clinically negative axilla following induction chemotherapy is currently underway.

publication date

  • January 1998



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1007/BF02303476

PubMed ID

  • 9869512

Additional Document Info

start page

  • 673

end page

  • 80


  • 5


  • 8