Herpesviruses in atherosclerosis and thrombosis: Etiologic agents or ubiquitous bystanders? Review uri icon

Overview

MeSH Major

  • Arteriosclerosis
  • Herpesviridae
  • Herpesviridae Infections
  • Thrombosis

abstract

  • The role of herpesvirus infections in the pathogenesis of vascular diseases remains an enigma. Although there is abundant circumstantial evidence of a role for herpesviruses in atherosclerosis and related processes, a cause-and-effect relationship has yet to be definitively established. This article will review the pathological, molecular, and biochemical evidence supporting the hypothesis that herpesviruses are involved in the development of atherosclerosis, restenosis after coronary angioplasty, accelerated atherosclerosis in recipients of heart transplants, and the induction of a prothrombotic phenotype in vascular endothelial cells.

publication date

  • March 31, 1998

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 9514401

Additional Document Info

start page

  • 339

end page

  • 48

volume

  • 18

number

  • 3