Fine-needle aspiration biopsy in the diagnosis and management of bone lesions: A study of 450 cases Academic Article Article uri icon


MeSH Major

  • Papanicolaou Test
  • Papillomavirus Infections
  • Uterine Cervical Neoplasms
  • Vaginal Smears


  • FNA biopsy of bone lesions is a reliable and easily performed diagnostic test for metastatic and primary bone tumors. False-positive results have major therapeutic implications, hence the significance of the authors' conservative diagnostic approach, which resulted in a false-positive rate of 0.2%. Areas of difficulty were due to inadequate sampling or misclassification with regard to the exact type of malignancy. The simplicity and accuracy of this procedure, which does not require any surgical incisions (open biopsy or manipulation), supports its important role in triaging and managing bone lesions with minimum risk or morbidity.

publication date

  • June 25, 1997



  • Academic Article


Digital Object Identifier (DOI)

  • 10.1002/(SICI)1097-0142(19970625)81:3<148::AID-CNCR4>3.0.CO;2-N

PubMed ID

  • 9196013

Additional Document Info

start page

  • 148

end page

  • 56


  • 81


  • 3