Glomerulomegaly and proteinuria in a patient with idiopathic pulmonary hypertension Academic Article uri icon

Overview

MeSH Major

  • Glomerulonephritis, Membranoproliferative
  • Hypertension, Pulmonary
  • Kidney Glomerulus
  • Nephrotic Syndrome
  • Proteinuria

abstract

  • Glomerulomegaly is a histologic finding present in idiopathic pulmonary hypertension, congenital cyanotic heart disease, morbid obesity associated with sleep apnea syndrome, sickle cell disease, and polycythemic states. This study examines the case of a 34-yr-old woman with idiopathic pulmonary artery hypertension who presented with nephrotic-range proteinuria. Kidney biopsy revealed enlarged glomeruli with mesangial-proliferative glomerulonephritis. A review of the pertinent literature and a discussion of the proposed pathophysiologic mechanisms leading to glomerulomegaly are presented.

publication date

  • January 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9402101

Additional Document Info

start page

  • 1966

end page

  • 70

volume

  • 8

number

  • 12