Glutathione S-transferase PI (GST-π) class expression by immunohistochemistry in benign and malignant prostate tissue Academic Article Article uri icon

Overview

MeSH Major

  • Nomograms
  • Prostate-Specific Antigen
  • Prostatic Neoplasms

abstract

  • Our study confirms the absence of GST-pi expression in prostate cancer and high grade PIN. Furthermore, GST-pi expression correlates well with the basal cell phenotype, but not with benign epithelial cells. The lack of staining among prostate cancer cells may reflect the absence of a basal cell layer, suggesting that GST-pi is involved more in epithelial differentiation and questioning its role in the malignant transformation of prostatic acinar cells.

publication date

  • February 1997

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0022-5347(01)65248-0

PubMed ID

  • 8996396

Additional Document Info

start page

  • 673

end page

  • 6

volume

  • 157

number

  • 2