Phase II randomized trial of gallium nitrate plus fluorouracil versus methotrexate, vinblastine, doxorubicin, and cisplatin in patients with advanced transitional-cell carcinoma Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Combined Chemotherapy Protocols
  • Carcinoma, Transitional Cell
  • Fluorouracil
  • Gallium
  • Urologic Neoplasms

abstract

  • Dose-intense M-VAC is superior to gallium nitrate/5-FU in poor-risk patients (P < .0001). Despite the overall high response rate, the median survival for patients with M-VAC remained unsatisfactory. Similar survival distributions were observed for patients who received investigational therapy followed by cisplatin-based therapy and patients treated with initial cisplatin-based therapy.

publication date

  • June 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9196161

Additional Document Info

start page

  • 2449

end page

  • 55

volume

  • 15

number

  • 6