Cancer incidence after retinoblastoma: Radiation dose and sarcoma risk Academic Article uri icon

Overview

MeSH Major

  • Eye Neoplasms
  • Neoplasms, Radiation-Induced
  • Neoplasms, Second Primary
  • Retinoblastoma
  • Sarcoma

abstract

  • Genetic predisposition has a substantial impact on risk of subsequent cancers in retinoblastoma patients, which is further increased by radiation treatment. A radiation dose-response relationship is demonstrated for all sarcomas and, for the first time in humans, for soft tissue sarcomas. Retinoblastoma patients should be examined for new cancers and followed into later life to determine whether their extraordinary cancer risk extends to common cancers of adulthood.

publication date

  • October 15, 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9333268

Additional Document Info

start page

  • 1262

end page

  • 7

volume

  • 278

number

  • 15