Adherence of mononuclear cells to endothelium in vitro is increased in patients with NIDDM Academic Article uri icon

Overview

MeSH Major

  • Diabetes Mellitus, Type 2
  • Endothelium, Vascular
  • Leukocytes, Mononuclear

abstract

  • Since the adherence of mononuclear cells to the endothelium represents the earliest step in atherogenesis, the observation that mononuclear cells from patients with NIDDM bind more avidly to cultured endothelial cells may help explain why accelerated atherosclerosis occurs in patients with NIDDM. The metabolic abnormality, or abnormalities, present in patients with NIDDM that is responsible for the enhanced adhesiveness of mononuclear cells requires further examination.

publication date

  • September 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 9283798

Additional Document Info

start page

  • 1462

end page

  • 5

volume

  • 20

number

  • 9