Pregnancy loss in the antiphospholipid-antibody syndrome - A possible thrombogenic mechanism Academic Article uri icon

Overview

MeSH Major

  • Abortion, Spontaneous
  • Annexin A5
  • Antibodies, Antiphospholipid
  • Antiphospholipid Syndrome
  • Blood Coagulation
  • Trophoblasts
  • Umbilical Veins

abstract

  • Antiphospholipid antibodies reduce the levels of annexin V and accelerate the coagulation of plasma on cultured trophoblasts and endothelial cells. The reduction of annexin V levels on vascular cells may be an important mechanism of thrombosis and pregnancy loss in the antiphospholipid-antibody syndrome.

publication date

  • July 17, 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1056/NEJM199707173370303

PubMed ID

  • 9219701

Additional Document Info

start page

  • 154

end page

  • 60

volume

  • 337

number

  • 3