Constipation in Parkinson's disease: Objective assessment and response to Psyllium Academic Article uri icon

Overview

MeSH Major

  • Cathartics
  • Constipation
  • Parkinson Disease
  • Psyllium

abstract

  • We evaluated the reliability of patient history and the effect of psyllium on symptoms and colorectal function in 12 patients with Parkinson's disease (PD) and constipation. In all but two, constipation anteceded the development of parkinsonian symptoms. A comparison with prospectively obtained stool diaries confirmed the patients' reported constipation in 7 of the 12 patients. Those patients with confirmed constipation had lower stool weights and reported more straining at stool. Measures of colonic and anorectal function were similar in those who were truly constipated and those who were not. Among those PD subjects with confirmed constipation, psyllium increased stool frequency and weight but did not alter colonic transit or anorectal function. We conclude that prospectively obtained stool diaries should be employed to confirm constipation in PD and that psyllium produces both subjective and objective improvements in constipation related to PD.

publication date

  • December 2, 1997

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/mds.870120617

PubMed ID

  • 9399219

Additional Document Info

start page

  • 946

end page

  • 51

volume

  • 12

number

  • 6