Arginine restores nitric oxide activity and inhibits monocyte accumulation after vascular injury in hypercholesterolemic rabbits
Academic ArticleArticle
Overview
MeSH Major
Education, Medical
Education, Medical, Continuing
Specialization
Vascular Diseases
abstract
We report that lesions induced by vascular injury in hypercholesterolemic animals are markedly reduced by oral administration of arginine. Moreover, we find that the nature of the lesion is altered, with a striking reduction in the percentage of macrophages comprising the lesion.