Efficacy of antibiotic prophylaxis for prevention of Lyme disease Review uri icon

Overview

MeSH Major

  • Antibiotic Prophylaxis
  • Bites and Stings
  • Ixodes
  • Lyme Disease

abstract

  • The available evidence to date suggests that the routine use of antibiotic prophylaxis for the prevention of Lyme disease remains uncertain. Meta-analysis of the controlled trials failed to establish definitive treatment efficacy owing to the small sample size of the combined trials and the low rates of infection following a deer tick bite. A larger randomized trial is needed to demonstrate definitively that prophylaxis is more effective than placebo in reducing the risk of early Lyme disease in endemic areas.

publication date

  • July 26, 1996

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 8803738

Additional Document Info

start page

  • 329

end page

  • 33

volume

  • 11

number

  • 6