A double-blind, placebo-controlled trial of desipramine for primary alcohol dependence stratified on the presence or absence of major depression Academic Article Article uri icon

Overview

MeSH Major

  • Cognitive Therapy
  • Depressive Disorder
  • Randomized Controlled Trials as Topic

abstract

  • Major depression secondary to alcohol dependence that is diagnosed after at least 1 week of abstinence can remain stable in some placebo-treated alcoholics and can respond to desipramine. Treating depression secondary to alcoholism may reduce risk for drinking relapse in some patients. Use of desipramine to reduce relapse in nondepressed alcoholics is not supported.

publication date

  • March 13, 1996

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1001/jama.275.10.761

PubMed ID

  • 8598592

Additional Document Info

start page

  • 761

end page

  • 7

volume

  • 275

number

  • 10