Signal transduction through lipid second messengers Article Report uri icon

Overview

MeSH Major

  • Apoptosis
  • Neoplasms

abstract

  • This review emphasizes the generation of glycerolipid and sphingolipid second messengers, and their molecular targets. The role of the phosphatidylinositol transfer protein and phospholipase D in signal transmission, and the structures of the 1, 2-diacylglycerol and calcium-binding sites of protein kinase C are discussed. Further, ceramide signaling through protein kinases and the role of cross-talk in the signaling of apoptosis and inflammation are addressed.

publication date

  • April 1996

Research

keywords

  • Report

Identity

Digital Object Identifier (DOI)

  • 10.1016/S0955-0674(96)80061-5

PubMed ID

  • 8791422

Additional Document Info

start page

  • 159

end page

  • 67

volume

  • 8

number

  • 2