Irinotecan is an active agent in untreated patients with metastatic colorectal cancer Academic Article uri icon

Overview

MeSH Major

  • Antineoplastic Agents, Phytogenic
  • Camptothecin
  • Colonic Neoplasms
  • Rectal Neoplasms

abstract

  • Irinotecan has activity in the treatment of patients with metastatic colorectal cancer. Strict adherence to an antidiarrheal regimen of diphenhydramine/loperamide significantly reduced the incidence of diarrhea; the agent was thereafter well tolerated in the majority of patients.

publication date

  • March 1996

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8622015

Additional Document Info

start page

  • 709

end page

  • 15

volume

  • 14

number

  • 3