Perineural invasion of prostate carcinoma cells is associated with reduced apoptotic index Academic Article Article uri icon

Overview

MeSH Major

  • Urologic Diseases
  • Urology

abstract

  • These results suggest that PN invasion by prostate carcinoma cells may not be only a volume effect of growing carcinomas; the neural components may favor the growth of carcinoma cells by inhibiting apoptosis, presumably through a paracrine mechanism, and thereby facilitate the spread of carcinoma cells along nerves. The data also suggest that heterogeneity in growth potential of prostate carcinoma cells may be determined by their local microenvironments, such as an association with neural components.

publication date

  • September 15, 1996

Research

keywords

  • Academic Article

Identity

Digital Object Identifier (DOI)

  • 10.1002/(SICI)1097-0142(19960915)78:6<1267::AID-CNCR15>3.0.CO;2-Z

PubMed ID

  • 8826950

Additional Document Info

start page

  • 1267

end page

  • 71

volume

  • 78

number

  • 6