Pathogenesis of the antiphospholipid antibody syndrome Review uri icon

Overview

MeSH Major

  • Antiphospholipid Syndrome

abstract

  • Endothelial and/or platelet activation likely initiates thrombus formation. Whether antiphospholipid antibody (aPL) is an activator, a toxic response, or a protective response is not clear, nor is it certain whether aPL is germ-line encoded or antigen-driven. The pregnancy model is particularly informative. Alternative hypotheses about thrombogenicity which relegate aPL to the role of bystander have not yet been excluded.

publication date

  • November 2, 1996

Research

keywords

  • Review

Identity

Language

  • eng

PubMed ID

  • 8902770

Additional Document Info

start page

  • 404

end page

  • 8

volume

  • 5

number

  • 5