'Osteoclastic' giant cell carcinoma of the pancreas: Report of a case with aspiration cytology Academic Article Article uri icon

Overview

MeSH Major

  • Comparative Genomic Hybridization
  • DNA Fragmentation

abstract

  • Multinucleate giant cells can be seen in pancreatic abscesses, fat necrosis, pseudocysts, tuberculosis, sarcoidosis and fungal infections. When the cells are associated with malignant epithelial cells, the differential diagnosis includes metastatic carcinoma, malignant melanoma, Hodgkin's disease, large cel anaplastic lymphoma, trophoblastic tumor, epithelioid sarcoma, malignant fibrous histiocytoma, angiosarcoma and rhabdomyosarcoma. Immunohistochemical stains, such as vimentin, S-100, leukocyte common antigen, human chorionic gonadotropin, Factor VII Ag, actin and desmin play an important role in differentiating between these lesions.

publication date

  • January 1996

Research

keywords

  • Academic Article

Identity

PubMed ID

  • 8842177

Additional Document Info

start page

  • 975

end page

  • 9

volume

  • 40

number

  • 5