Use of an anti-ras ribozyme to alter the malignant phenotype of a human bladder cancer cell line Academic Article uri icon

Overview

MeSH Major

  • RNA, Catalytic
  • Urinary Bladder Neoplasms

abstract

  • This study suggests that the invasive phenotype is blunted with the anti-ras ribozyme, delaying but not abolishing the metastatic phenotype. These results further delineate the roles of ras genes in malignancy and demonstrate that ribozymes may be a powerful tool for exploring the role of individual oncogenes and may be used as anticancer agents.

publication date

  • September 1996

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8709343

Additional Document Info

start page

  • 1186

end page

  • 8

volume

  • 156

number

  • 3