Tumor necrosis factor-α and tumor necrosis factor receptors in the failing human heart Academic Article uri icon

Overview

MeSH Major

  • Heart Failure
  • Receptors, Tumor Necrosis Factor
  • Tumor Necrosis Factor-alpha

abstract

  • In summary, the results of this study constitute the initial demonstration that TNF receptor proteins are dynamically regulated in patients with advanced congestive heart failure. Moreover, the observation that failing hearts express elevated levels of TNF-alpha suggests that overexpression of this cytokine may be one of several different maladaptive mechanisms responsible for the progressive cardiac decompensation that occurs in advanced heart failure.

publication date

  • February 15, 1996

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8640999

Additional Document Info

start page

  • 704

end page

  • 11

volume

  • 93

number

  • 4