Relations between left ventricular hypertrophy and systemic arterial disease in essential hypertension
Diabetes Mellitus, Type 2
Hypertrophy, Left Ventricular
The presence of either electrocardiographic or echocardiographic evidence of left ventricular hypertrophy is associated with an increased risk of cardiovascular events among hypertensive patients and in the general population. Whereas the risk of complications from ischemic heart disease is increased among individuals with ventricular hypertrophy, recent data suggest that systemic arterial disease and its clinical consequences are also more prevalent in individuals with ventricular hypertrophy. This article reviews the available data on the relationship between left ventricular hypertrophy and noncoronary arterial disease, including structural and functional abnormalities of both the resistance and conduit vessels. The contribution of alterations in arterial properties to the development of left ventricular hypertrophy, the combined association of ventricular and vascular hypertrophy, and the prognostic significance of vascular hypertrophy will be discussed.