Age-related changes in brain: I. Magnetic resonance imaging measures of temporal lobe volumes in normal subjects Academic Article uri icon

Overview

MeSH Major

  • Aging
  • Magnetic Resonance Imaging
  • Temporal Lobe

abstract

  • The volume of temporal lobe structures was examined in twenty-seven older (mean age of 69.2 +/- 8.3 years) and ten younger subjects (mean age of 26.1 +/- 4.1 years) using quantitative magnetic resonance imaging (MRI) methods. Multiple regression analysis, using gender, overall atrophy, and head size as covariates, showed unique contributions of age to variance in both medial and lateral temporal lobe volumes. Temporal lobe subregions that showed the strongest unique age-related reductions were the hippocampus, fusiform gyrus, and parahippocampus. These results suggest age-related reductions in temporal lobe subvolumes.

publication date

  • December 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1007/BF02238754

PubMed ID

  • 8584590

Additional Document Info

start page

  • 343

end page

  • 55

volume

  • 66

number

  • 4