Interferon-gamma-induced oligodendrocyte cell death: Implications for the pathogenesis of multiple sclerosis Academic Article uri icon

Overview

MeSH Major

  • Apoptosis
  • Interferon-gamma
  • Interleukin-6
  • Multiple Sclerosis
  • Oligodendroglia

abstract

  • Injury to a substantial number of oligodendrocytes in MS is the results of programmed cell death rather than necrotic cell death mechanisms. We postulate that IFN gamma plays a role in the pathogenesis of MS by activating apoptosis in oligodendrocytes.

publication date

  • November 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC2230017

PubMed ID

  • 8612196

Additional Document Info

start page

  • 732

end page

  • 43

volume

  • 1

number

  • 7