Basal ganglia phantom simulation: improvement of relative quantitation in SPECT [I-123] dynamic neuroreceptor imaging Conference Paper uri icon

Overview

MeSH Major

  • Biomarkers, Tumor
  • Cone-Beam Computed Tomography
  • Databases as Topic
  • Lung Neoplasms

abstract

  • The [I-123] labeled radiopharmaceuticals are being used to study neuroreceptors in monkey and human brain with a triple headed SPECT system. To optimized the quantitative accuracies of the monkey dynamic neuroreceptor studies, a combination of collimators - high-resolution fan-beam collimators (HRF), ultra HRF (UHRF), a count rate dependent 2-D Wiener (2-DW) prefiltering, 3-D Wiener postfiltering techniques (3-DW) is studied. The acquisition parameters are designed to simulate the dynamic neuroreceptor studies in the monkey. The results indicate that the UHRF with 3-DW improves images quantization in SPECT neuroreceptor imaging.

publication date

  • January 1995

Research

keywords

  • Conference Paper

Additional Document Info

start page

  • 1730

end page

  • 1734

volume

  • 4