Gender-specific criteria and performance of the exercise electrocardiogram
At high specificity, gender-specific test partitions improve sensitivity of the ST/HR slope for the identification of coronary disease in women, with no decrease in sensitivity in men. In contrast, gender-specific partitions do not change performance of standard test criteria, which is lower in women than in men. Accordingly, the relative benefit of heart rate adjustment by the ST/HR slope method is greater in women than in men. These findings support use of the ST/HR slope with use of gender-specific partitions for the identification and quantification of coronary artery disease in both men and women.