Expression and functional significance of tumor necrosis factor receptors in human myocardium Academic Article uri icon

Overview

MeSH Major

  • Myocardium
  • Receptors, Tumor Necrosis Factor

abstract

  • Results of the present study show that the adult human heart expresses both mRNA and receptor proteins for TNFR1 and TNFR2; moreover, the negative inotropic effects of TNF-alpha in adult cardiac myocytes appear to be initiated by activation of TNFR1.

publication date

  • January 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7664431

Additional Document Info

start page

  • 1487

end page

  • 93

volume

  • 92

number

  • 6