Fibrinolysis inhibits shear stress-induced platelet aggregation Academic Article uri icon

Overview

MeSH Major

  • Fibrinolysis
  • Platelet Aggregation

abstract

  • These results demonstrate that TPA inhibits platelet aggregation in response to pathological shear stress by altering the multimeric composition of vWf. This effect of TPA on shear stress-induced platelet aggregation may contribute, along with fibrinolysis, to the therapeutic effect of TPA in restoring blood flow during acute coronary artery thrombosis.

publication date

  • January 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7664419

Additional Document Info

start page

  • 1399

end page

  • 407

volume

  • 92

number

  • 6