Cognitive effects after epidural vs general anesthesia in older adults: A randomized trial Academic Article uri icon

Overview

MeSH Major

  • Anesthesia, Epidural
  • Anesthesia, General
  • Cognition Disorders
  • Elective Surgical Procedures
  • Postoperative Complications

abstract

  • The type of anesthesia, general or epidural, does not affect the magnitude or pattern of postoperative cognitive dysfunction or the incidence of major cardiovascular complications in older adults undergoing elective total knee replacement. This is the largest trial of the effects of general vs regional anesthesia on cerebral function reported to date, with more than 99% power to detect a clinically significant difference on any of the neuropsychological tests.

publication date

  • January 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7791257

Additional Document Info

start page

  • 44

end page

  • 50

volume

  • 274

number

  • 1