Teniposide for brain metastases of small-cell lung cancer: A phase II study Academic Article uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Carcinoma, Small Cell
  • Lung Neoplasms
  • Teniposide

abstract

  • Teniposide is active against brain metastases of SCLC. It is a suitable drug for palliation, especially of patients without extensive pretreatment and with a good neurologic function and performance status. Patients previously treated with cranial radiotherapy are also candidates for this therapy. If systemic chemotherapy is considered for tumor progression outside the brain, radiotherapy of brain metastases might be omitted or delayed pending the effect of chemotherapy. The use of corticosteroids in patients with brain metastases treated with chemotherapy might influence the efficacy of the chemotherapy.

publication date

  • January 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1200/JCO.1995.13.3.660

PubMed ID

  • 7884426

Additional Document Info

start page

  • 660

end page

  • 5

volume

  • 13

number

  • 3