The hippocampus in aging and Alzheimer's disease Article Report uri icon


MeSH Major

  • Alzheimer Disease
  • Choroid
  • Hippocampus
  • Supranuclear Palsy, Progressive
  • Tomography, X-Ray Computed


  • The role of imaging in the evaluation of neurodegenerative disorders is summarized. The primary role of imaging is to exclude potentially treatable disorders such as meningioma, extracerebral hematoma. Wernicke's disease, and hypothyroidism. Atrophic changes dominate in the hippocampal region on Alzheimer's disease versus the anterior, frontal, and temporal lobes in Pick's disease. Signal hypointensity in the putamen on T2-weighted spin-echo images favors poorly drug-responsive Parkinson's disease whereas putaminal hyperintensity is observed with Creutzfeld-Jacob, Wilson's, and Leigh's diseases. As our population ages, a thorough understanding of imaging findings in a geriatric population assumes an increasing importance.

publication date

  • January 1995



  • Report


PubMed ID

  • 7743078

Additional Document Info

start page

  • 1

end page

  • 17


  • 5


  • 1