Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty Academic Article uri icon

Overview

MeSH Major

  • Angioplasty, Balloon, Coronary
  • Antibodies, Monoclonal
  • Coronary Disease
  • Immunoglobulin Fab Fragments
  • Platelet Aggregation
  • Platelet Aggregation Inhibitors

abstract

  • This study demonstrates that c7E3 Fab is a potent inhibitor of SIPA, which may be an important mechanism of its beneficial effect in the treatment of arterial occlusive diseases and in the prevention of thrombotic complications of coronary artery disease after angioplasty.

publication date

  • March 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7867183

Additional Document Info

start page

  • 1427

end page

  • 31

volume

  • 91

number

  • 5