Molecular and cytogenetic studies in the diagnosis of patients with poorly differentiated carcinomas of unknown primary site Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Carcinoma
  • Chromosome Aberrations
  • Germinoma
  • Neoplasms, Unknown Primary

abstract

  • Molecular and cytogenetic studies are useful in establishing specific diagnoses in patients with poorly differentiated carcinomas of unknown primary site. This group of tumors is heterogeneous and is composed of germ cell tumors, melanoma, lymphoma, neuroepithelioma, and desmoplastic small-round-cell tumor in addition to some that are not yet classifiable. Response to cisplatin therapy correlates with the finding of i(12p) in tumor by either molecular or cytogenetic studies.

publication date

  • January 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 7799031

Additional Document Info

start page

  • 274

end page

  • 82

volume

  • 13

number

  • 1