Acquired von Willebrand's syndrome causing a hemorrhagic diathesis in a patient with hypothyroidism Academic Article uri icon

Overview

MeSH Major

  • Gingival Hemorrhage
  • Hypothyroidism
  • von Willebrand Diseases

abstract

  • The occurrence of bleeding diathesis with menorrhagia and easy bruising may occur in patients with moderate to severe hypothyroidism sometimes linked to acquired von Willebrand's disease (VWD). We describe a patient with profound hypothyroidism in whom the diagnosis of hypothyroidism was established while evaluating uncontrolled gingival bleeding after a dental procedure. Thyroid hormone replacement led to a rise in von Willebrand factor, factor VIIIC, and a significant fall in the elevated bleeding time from 15 to 8 min. Acquired von Willebrand's disease is an unusual manifestation of hypothyroidism and is reversible.

publication date

  • January 1995

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8563480

Additional Document Info

start page

  • 399

end page

  • 401

volume

  • 5

number

  • 5