Diagnosis and treatment of primary hyperaldosteronism Academic Article Article uri icon

Overview

MeSH Major

  • Angiotensins
  • Antihypertensive Agents
  • Blood Pressure
  • Extracellular Fluid
  • Renin
  • Renin-Angiotensin System
  • Sodium

abstract

  • Of the 51 patients with primary aldosteronism who had adrenalectomy (43 patients with adenomas and 8 with hyperplasia), those most likely to be cured were younger and had lower plasma renin activity. In patients with adenomas who were cured or improved, aldosterone secretion was more likely to lateralize. Tests that distinguished adenomas from adrenal hyperplasia included the postural stimulation test, urinary excretion rates of 18-oxocortisol and 18-hydroxycortisol, and adrenal vein sampling.

publication date

  • December 1994

Research

keywords

  • Academic Article

Identity

PubMed ID

  • 7978702

Additional Document Info

start page

  • 877

end page

  • 85

volume

  • 121

number

  • 11