Chemical and mechanical degradation of UHMWPE: Report of the development of an in vitro test Academic Article uri icon


MeSH Major

  • Cell Membrane
  • Membrane Transport Proteins
  • Molecular Dynamics Simulation
  • Sterols


  • The development of an in vitro test to examine the combined effects of chemical environment and cyclic loading history on the chemical, physical and mechanical properties of ultrahigh molecular weight polyethylene (UHMWPE), used in total joint replacement implants, is reported. The appropriate control and degrading environments were determined by maintaining gamma radiation sterilized UHMWPE for up to 6 months in aqueous environments of distilled water and three concentrations of hydrogen peroxide in distilled water. Specimens were evaluated by infrared spectroscopy.

publication date

  • March 1994



  • Academic Article

Additional Document Info

start page

  • 17

end page

  • 21


  • 5


  • 1