Dose-ranging evaluation of the serotonin antagonist dolasetron mesylate in patients receiving high-dose cisplatin Academic Article uri icon

Overview

MeSH Major

  • Antiemetics
  • Cisplatin
  • Indoles
  • Quinolizines
  • Serotonin Antagonists

abstract

  • Dolasetron mesylate can be administered safely at doses up to 5.0 mg/kg, with comparable complete protection rates and increased adverse effects at doses greater than 2.4 mg/kg. Antiemetic activity was seen after cisplatin. Trials comparing single infusions of dolasetron mesylate and ondansetron are under way.

publication date

  • May 1994

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed ID

  • 8164028

Additional Document Info

start page

  • 1045

end page

  • 9

volume

  • 12

number

  • 5